e-mail                     doctordoctorkk@yahoo.com.tw

Education

Professional experience:

Conferences

1. Hsieh C.-F., Horng J.-T., Studies of enterovirus 71 replication and autophagy. Host-Microbes Interactions, Hsinchu, Taiwan, July 2007 (Poster).
2. Hsieh C.-F., Horng J.-T., Studies of enterovirus 71 replication and autophagy. The 1^st International Symposium on RNA Viruses, Taoyuan, Taiwan, December 2010 (Poster).
3. Hsieh C.-F., Lin T.-J., Tsai Y.-H., Chang H.-W., Horng J.-T., Studies on the anti-influenza virus mechanism of MHKST (MA-HSING-KAN-SHIH-TANG) and CFPTS (CHING-FANG-PAI-TU-SAN). The 2^nd International Symposium on RNA Viruses, Virus-Host Interactions, Taoyuan, Taiwan, November 2011 (Poster).
4. Hsieh C.-F., Lo C.-W., Liu C.-H., Lin S.-M., Yen H.-R., Lin T.-Y., Horng J.-T., Mechanism by which ma-xing-shi-gan-tang inhibits the entry of influenza virus. The 31^st Annual Meeting-American Society for Virology, Wisconsin, Ammerica, 2012 (Poster).
5. Hsieh C.-F., Horng J.-T., Mechanism by which ma-xing-shi-gan-tang inhibits the entry of influenza virus. The 3^rd International Symposium on RNA Viruses, Virus-Host Interactions, Taoyuan, Taiwan, November 2012 (Poster)
6. Chung-Fan Hsieh, Jin-Yuan Ho, Chwan-Fwu Lin, Chun-Hsun Huang and Jim-Tong Horng. An extract from Taxodium distichum targets hemagglutinin- and neuraminidase-related activities of influenza virus in vitro. 10^th Asia-Pacific Congress of Medical Virology 2015 (Poster) 
7. Chung-Fan Hsieh, Jin-Yuan Ho, Chwan-Fwu Lin, Chun-Hsun Huang and Jim-Tong Horng. An extract from Taxodium distichum targets hemagglutinin- and neuraminidase-related activities of influenza virus in vitro. 6^th 2016 International Symposium on Infectious Disease and Signal Transduction and 2016 Taiwan-Japan Joint Symposium on Cell Signaling and Gene Regulation (Poster)
8. Chung-Fan Hsieh, Yu-Li Chen, Cheng-Hsun Chiu, Pei-Wen Hsieh and Jim-Tong Horng. Using natural product-based inhibitor (CGU-V007) to dissect enterovirus 71 replication. International Union of Microbiological Societies (IUMS) 2017(Oral)

Bibliography

1. Ku T.-C., Huang Y.-N., Huang C.-C., Yang D.-M., Kao L.-S., Chiu T.-Y., Hsieh C.-F., Wu P.-Y., Tsai Y.-S., Lin C.-C. (2007). An automated tracking system to measure the dynamic properties of vesicles in living cells. Microscopy Research and Technique 70(2),119-34.
2. Wu M.-S., Yen H.-R., Chang C.-W., Peng T.-Y., Hsieh C.-F., Chen C.-J., Lin T.-Y., Horng J.-T. (2011). Mechanism of action of the suppression of influenza virus replication by Ko-Ken Tang through inhibition of the phosphatidylinositol 3-kinase/Akt signaling pathway and viral RNP nuclear export. Journal of Ethnopharmacology 134(3):614-23.
3. Hsu J.-T., Yeh J.-Y., Lin T.-J., Li M.-L., Wu M.-S., Hsieh C.-F., Chou Y.-C., Tang W.-F., Lau K.-S., Hung H.-C., Fang M.-Y., Ko S., Hsieh H.-P., Horng J.-T. (2012) Identification of BPR3P0128 as an inhibitor of cap-snatching activities of influenza virus. Antimicrobial Agents and Chemotherapy 56(2):647-57.
4. Liu C.-H., Horng J.-T., Chang J.-S., Hsieh C.-F., Tseng Y.-C., Lin S.. (2012). Localization and force analysis at the single virus particle level using atomic force microscopy. Biochemical and Biophysical Research Communications 417(1):109-15.
5. Chen M.-C., Chen H.-Y., Lin C.-Y., Chien C.-H., Hsieh T.-F., Horng J.-T., Qiu J.-T., Huang C.-C., Ho C.-H., Yang F.-L.. (2012). A CMOS-compatible poly-Si nanowire device with hybrid sensor/memory characteristics for System-on-Chip applications. Sensors 3952-63.
6. Hsieh C.-F.*, Lo C.-W., Liu C.-H., Lin S., Yen H.-R., Lin T.-Y., Horng J.-T.. (2012). Mechanism by which ma-xing-shi-gan-tang inhibits the entry of influenza virus. Journal of Ethnopharmacology 143(1):57-67.
7. Hsieh C.-F.*, Yen H.-R., Liu C.-H., Lin S., Horng J.-T. (2012). Ching-fang-pai-tu-san inhibits the release of influenza virus. Journal of Ethnopharmacology 144(3):533-44
8. Ho JY, Chang HW, Lin CF, Liu CJ, Hsieh CF, Horng JT. (2014). Characterization of the anti-influenza activity of the Chinese herbal plant Paeonia lactiflora. Viruses 6(4):1861-75.
9. Ho JY, Chern JH, Hsieh CF, Liu ST, Liu CJ, Wang YS, Kuo TW, Hsu SJ, Yeh TK, Shih SR, Hsieh PW, Chiu CH, Horng JT.(2016). In vitro and in vivo studies of a potent capsid-binding inhibitor of enterovirus 71. Journal of Antimicrobial Chemotherapy 71(7):1922-32.(本人為共同第一作者)
10. Hsieh CF*, Chen YL, Lin CF, Ho JY, Huang CH, Chiu CH, Hsieh PW, Horng JT. (2016)An extract from Taxodium distichum targets hemagglutinin- and neuraminidase-related activities of influenza virus in vitro. Scientific Reports 31;6:36015.
11. Hong CH, Hsieh CF, Tseng CS, Huang WC, Guo CY, Lin S, Lee SC.(2017) A nanobiosensing method based on force measurement of antibody-antigen interaction for direct detection of enterovirus 71 by the chemically modified atomic force microscopic probe. Microbial pathogenesis Volume 111, Pages 292-297
12. Sethy B, Hsieh CF, Chieh Y, Horng JT, Hsieh PW(2018) Design, synthesis and structure-activity relationships of a new class of anti-human enterovirus D68 and A71 agents. Future Medicinal Chemistry 10(11):1333-1347
13. Sethy B, Hsieh CF, Lin TJ, Hu PY, Chen YL, Lin CY, Tseng SN, Horng JT, Hsieh PW(2019, Feb). Design, Synthesis, and Biological Evaluation of Itaconic Acid Derivatives as Potential Anti-Influenza Agents. Journal of medicinal chemistry, 62 (5), pp 2390–2403
14. Hsieh CF*, Jheng JR, Lin GH, Chen YL, Ho JY, Liu CJ, Hsu KY, Chen YS, Chan YF, Yu HM, Hsieh PW, Chern JH, Horng JT (2020, Dec). Rosmarinic acid exhibits broad anti-enterovirus A71 activity by inhibiting the interaction between the five-fold axis of capsid VP1 and cognate sulfated receptors. Emerging microbes & infections, (1):1194-1205.